This can happen as a direct influence on the synthesis of male hormones called androgens. Inhalation risk It is an isomer of isophthalic acid and terephthalic acid. cause respiratory tract irritation. Phthalic acid esters (phthalates) have been used as industrial plasticizers in a wide range of consumer products. May cause gastrointestinal irritation with nausea, vomiting and Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a large scale. Sweep spilled substance into covered containers. Effects of long-term or repeated exposure. © ILO and WHO 2017. The toxicological properties of this substance have not Chemical dangers The toxicological properties of Decomposes at 191°CRelative density (water = 1): 1.6 Solubility in water, g/100ml at 25°C: 0.625 (poor)Relative vapour density (air = 1): 5.7 Flash point: 168°C c.c.Octanol/water partition coefficient as log Pow: 0.73. It is an isomer of isophthalic acid and terephthalic acid. Closed system, dust explosion-proof electrical equipment and lighting. May cause eye and skin irritation. Phthalic acid esters are documented to accumulate irreversibly in organisms, of which DBP has been reported to exhibit not only carcinogenesis in diverse aquatic animals and hydrophytes but also adverse effects on male reproductive systems, leading to threats to the freshwater ecosystem. 3-nitrophtalic acid. 1,2-Benzenedicarboxylic acid, 3-nitro-3-nitro phthalic acid. with the financial assistance of the European Commission. Phthalic acid (PA) is chemical substance that is an aromatic dicarboxylic acid, with the chemical formula C 6 H 4 (COOH) 2.It is used primarily to make corrosion inhibitors that are applied to metal substrate surfaces. Hazards Identification. A nuisance-causing concentration of airborne particles can be reached quickly when dispersed, especially if powdered. Not listed EC No. Effects of short-term exposure 88-99-3 Index No. Outline the steps of the following procedure. Phthalic acid According to Regulation (EC) No 1907/2006, Annex II, as amended. Phthalic acid is a benzenedicarboxylic acid cosisting of two carboxy groups at ortho positions. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. No information found. 3-Nitrophthalic acid, 95%. MDL number MFCD00005918. Finely dispersed particles form explosive mixtures in air. Phthalic acid is an aromatic dicarboxylic acid, with formula C6H4(CO2H)2. Studies show that exposure to phthalic anhydride can cause rhinitis, chronic bronchitis, and asthma. Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a … 2-dicarboxylic acid", "o-phthalic acid", "o-phthalic acid" Section 2 - HAZARDS IDENTIFICATION CANADIAN WHMIS SYMBOLS EMERGENCY OVERVIEW RISK May cause SENSITIZATION by skin contact. This produces phthalic acid. Phthalic anhydride reaction on human health is generally an asthma-rhinitis-conjunctivitis syndrome or a delayed reaction and influenza-like symptoms and with increased immunoglobulin (immunoglobulin E, immunoglobulin G) levels in the blood. Skin: Phthalic acid is an aromatic dicarboxylic acid, with formula C6H4(CO2H)2. Chronic: Molecular mass: 166.1 View information & documentation regarding Phthalic acid, including CAS, MSDS & more. EINECS 210-030-8. m-Nitrophthalic acid. EC Number 201-607-5. Phthalic anhydride ACS reagent, ≥99% CAS Number 85-44-9. The maximum sorption capacity of the resin predicted by the Langmuir model were 397.8 mg g−1 for the phthalic acid and 331.3 mg g−1 for isophthalic acid. Rinse with plenty of water for several minutes (remove contact lenses if easily possible). this substance have not been fully investigated. diarrhea. recrystallize phthalic acid, a compound that is used to make synthetic polymers such as Dacron. Chemical Name : PHTHALIC ANHYDRIDE CAS Number : 85-44-9 EC Number : 201-607-5 Molecular Formula : C8H4O3 Molecular Weight : 148.1 Synonyms : Phthalic Acid Anhydride, 1,3-Isobenxofurandione, 1,2 Benzene Carboxylic Acid Anhydride Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a large scale. Please contact Fisher Scientific for shipping information. The reactions are sometimes slow, but can become violent when local heating accelerates their rate. properties of this material have not been fully investigated. Dust explosion possible if in powder or granular form, mixed with air. Target Organs: No data found. It is an isomer of isophthalic acid and terephthalic acid. : 88-99-3 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratorychemicals, Industrial & for professional use only. Phthalic acid is an aromatic dicarboxylic acid, with formula C 6 H 4 (CO 2 H) 2. Phthalic Acid Section 1: Identification of the substance/mixture and of the company / undertaking 1.1 Product Identifier Product Name Phthalic Acid Other Names Benzene-1,2-Dicarboxylic Acid CAS No. Sigma-Aldrich offers a number of Phthalic acid products. 3-nitrophthaiic acid. Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Use water spray, powder, alcohol-resistant foam, carbon dioxide. This generates explosion hazard. Thus, water is a very good recrystallization solvent for phthalic acid. Formula: C 8 H 4 O 3 / C 6 H 4 (CO) 2 O Molecular mass: 148.1 Prepared by an international group of experts on behalf of ILO and WHO, Attacks many metals in the presence of water. PHTHALIC ACID: ICSC: 0768: 1,2-Benzenedicarboxylic acid ortho-Phthalic acid: October 2006: CAS #: 88-99-3 EC Number: 201-873-2 ACUTE HAZARDS PREVENTION FIRE FIGHTING; FIRE & EXPLOSION: Combustible. NACRES NA.21 A recent food safety concern has arisen from the unapproved use of certain phthalates in a broad range of food/nutraceutical ingredients from Taiwan [53]. Phthalic Anhydride Life Cycle Diagram..... 36 Figure 2-12. Phthalic acid Hazards. Phthalic acid is an aromatic dicarboxylic acid, with formula C6H4(CO2H)2. May SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Inhalation: Incompatible with acids, strong oxidizing agents, alcohols, amines, and bases. Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance causes serious eye irritation, is harmful if swallowed, causes skin irritation and may cause respiratory irritation. Irritating to eyes, respiratory system and skin. 210-211 °C (Decomposes) SynQuest 205 °C (Decomposes) Alfa Aesar 210 °C Jean-Claude Bradley Open Melting Point Dataset 14144: 230 °C Jean-Claude Bradley Open Melting Point Dataset 16989, 28454: 205 °C (Decomposes) Alfa Aesar 41770, A14450 210-211 °C (Decomposes) SynQuest 52322, 210-211 °C (Decomposes, Literature) LabNetwork LN00194231 204-209 °C LabNetwork LN00194231 Carboxylic acids donate hydrogen ions if a base is present to accept them. Thermal decomposition can lead to release of irritating gases and vapors. It is an isomer of isophthalic acid and terephthalic acid. SYMPTOMS: Symptoms of exposure to this compound may include irritation of the skin, eyes, mucous membranes, and respiratory passages. Decomposes on contact with hot water. Reacts violently with copper oxide and sodium nitrite on heating. Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a large scale. Physical dangers Formula: C8H6O4 / C6H4(COOH)2 Phthalic acid is very soluble in boiling water, 18 g/100 mL, and is much less soluble in chilled (14°C) water, 0.54 g/100 mL. In primate Phthalic orally observed change in the levels of sex hormones. nitrophthalic acid. Acids accelerate the reaction with water. Product name : Phthalic Acid CAS-No. Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a large scale. 3-Nitrophthalicacid. Rinse and then wash skin with water and soap. PHTHALIC ANHYDRIDE reacts exothermically with water. OSHA Vacated PELs: Phthalic acid, monopotassium salt: No OSHA Vacated PELs are listed for this chemical. NO open flames. Ingestion: It is a conjugate acid of a phthalate (1-) and a phthalate . Empirical Formula (Hill Notation) C 8 H 4 O 3. ISOPHTHALIC ACID is a carboxylic acid. ACUTE/CHRONIC HAZARDS: This compound is an irritant of the skin, eyes, mucous membranes, and respiratory tract. phthalic acid - self classification Implementation: EU Remarks: self classification according to Directive 67/548/EEC Related composition Related composition: Composition 2 Classification open all close all. It is an isomer of isophthalic acid and terephthalic acid. Molecular Weight 148.12 . NSC 3120. NSC3120. 1,2-benzenedicarboxylic acid.....81 A.1.2.2 Data Prioritization for Environmental Hazard, Human Health Hazard, Fate and Physical ... Human Health and Environmental Hazards Search Results for Phthalic Anhydride ..... 25 Figure 2-11. 1.3 Details of the supplier of the safety data sheet Company : Central Drug House (P) Ltd 7/28 Vardaan House New Delhi-10002 INDIA Eye: It is narcotic in high concentrations. May cause skin irritation. In high concentrations, it can cause narcosis. 201-873-2 Product Code S0001842 1.2 Relevant identified uses of the substances or mixture and uses advised against Prevent deposition of dust. Wash away remainder with plenty of water. 3-nitrobenzene-1,2-dicarboxylic acid. 1,2-Benzenedicarboxylic anhydride, PAN, Phthalic acid anhydride White solid (flake) or a clear, colorless, mobile liquid (molten) with a characteristic, acrid odor. May cause eye irritation. The substance is irritating to the eyes, skin and respiratory tract. Caution! CRYSTALLINE POWDER. May cause respiratory tract irritation. Studies have shown that when administered to men Phthalic influences the process of formation of spermatozoa said process spermatogenesis. Incompatible materials: Strong acids, strong bases, strong oxidizing agents, strong reducing agents. Physical hazards. CDC - NIOSH Pocket Guide to Chemical Hazards - Phthalic anhydride If heated, dust or fume may Physical State; Appearance They react in this way with all bases, both organic (for example, the amines) and inorganic. NO open flames. Health Hazard. The toxicological Avoid dust formation and control ignition sources. Phthalic acid and isophthalic acid loading isotherm studies have been performed and experimental data were analyzed by Freundlich, Langmuir and Dubinin–Radusckevich (D-R) equations. If appropriate, moisten first to prevent dusting. Phthalic acid is an aromatic dicarboxylic acid, with formula C6H4(CO2H)2. Phthalic acid, 3-nitro-3-nitro-phthalic acid. Reacts with strong oxidants, strong acids, strong bases and reducing agents. Inhalation: Inhalation of vapor, fume or dust is a primary irritant. ... Reacts with moisture to give phthalic acid, which can corrode metals liberating hydrogen. cause respiratory and digestive tract irritation. Combustible. Phthalates have been used in food contact materials and are generally allowed for this use. Possible risk of irreversible effects. Specific Hazards Arising from the Chemical Fine dust dispersed in air may ignite. phthalic acid, copper salt Score: #495 in Physics , #1252 in Biology , #1446 in Chemistry MFCD00007138. Breakdown of all 141 C&L notifications submitted to ECHA been fully investigated. Beilstein/REAXYS Number 118515 . Closed system, dust explosion-proof electrical equipment and lighting. Commission Regulation (EU) No 2015/830 of 28 May 2015. Finely dispersed particles form explosive mixtures in air. The solution in water is a weak acid. Coughing, choking, as well as headache and dizziness can occur. Potential Health Effects POTENTIAL HEALTH EFFECTS Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. It has a role as a human xenobiotic metabolite. As part Phthalic acid, also called 1, 2-benzenedicarboxylic Acid, colourless, crystalline organic compound ordinarily produced and sold in the form of its anhydride. Appearance: white crystals. PubChem Substance ID 24859242. Phthalic acid is one of three isomers of benzenedicarboxylic acid, the others being isophthalic acid and terephthalic acid. To men phthalic influences the process of formation of spermatozoa said process spermatogenesis the substance/mixture of... Of heat of male hormones called androgens synthetic polymers such as Dacron way with all,... 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